The European Investment Bank (EIB) and Angelini Ventures – Angelini Industries’ corporate venture capital fund – have signed an agreement to provide a total of €150 million in financing for European biotechnology and digital health startups. This is the first agreement the EIB has signed with a corporate venture capital in healthcare sector, and states that Angelini Ventures and the EIB will each invest €75 million over the next six years.

Under the agreement, the EIB and Angelini plan to co-invest in a total of seven to ten European startups developing innovative solutions particularly suited for market launch, in areas such as biotechnology, medical technology and digital health.

“Initiatives like this strengthen Europe’s ability to lead technological innovation and generate tangible benefits for people, patients and businesses,” said EIB Vice-President Gelsomina Vigliotti. “Investing in biotechnology and digital health is vital, as it accelerates research, improves the quality of care, and supports the growth of companies able to bring cutting-edge solutions to market.”

Presented at the Angelini Ventures head office in Rome today, the initiative is aligned to TechEU, the EIB Group’s investment programme to strengthen the growth of innovation and technological leadership in Europe. Via TechEU, the EIB Group aims to invest €70 billion in equity, quasi-equity, loans and guarantees over the three-year period from 2025 to 2027, with the goal of mobilising €250 billion of investment in the real economy. The agreement also strengthens Angelini Ventures’ position in the sector. Founded in 2022 with €300 million from Angelini Industries (an Italian multinational in the health, industrial technology and consumer goods sectors), the company has already invested €125 million in 22 startups.

“This important agreement with the EIB enables us to bring our group’s commitment to innovation through venture capital to a European strategic context,” said Angelini Industries CEO Sergio Marullo di Condojanni. “Being chosen by the EIB for an ambitious project aiming to consolidate Europe’s role in innovation and health is an opportunity to work towards the common goal of turning researchers’ excellent ideas into products and services with a positive impact on people’s lives and the economic development of European countries.”

“The agreement with the EIB is a key step in strengthening our international presence and global vision,” explained Angelini Ventures CEO Paolo Di Giorgio. “This development path is essential to accelerating market access for talent and innovative projects, facilitating strategic partnerships in health and offering scaling opportunities for investments and partners. These elements are fundamental to speeding up growth and creating value in the healthcare and biotechnology sector, promoting European innovation, competitiveness and social impact on an international level.”

As a first step of the new partnership, Angelini Ventures and the EIB intend to co-invest in the second financing round of Adcytherix, a French biopharmaceutical company that develops innovative ADCs (Antibody-Drug Conjugates), with the investment agreement currently being finalized. These targeted therapies combine antibodies with next-gen cytotoxic payloads, to enhance precision, reduce toxicity and address resistance to current treatments. The first round, which closed in October of this year, was led by Bpifrance through its Large Venture and InnoBio investment strategies, and co-led by Kurma Partners, Andera Partners and Angelini Ventures.

Startups in Europe and Italy

The European Commission Startup and Scale Up Strategy aims to more effectively overcome the two main obstacles that startups face as they grow: the transition from research to development and the market, and the leap from startup to established company. In this domain, the work of the European Investment Bank Group (EIB Group) with corporate venture capital companies helps to facilitate the identification and financing of innovative businesses, with the potential to accelerate the growth, scalability and competitiveness of European startups via greater availability of capital. Another goal is to stimulate a potential European initial public offering (IPO) market, which would help increase the business relevance of European stock exchanges and help to keep value generated within Europe, in Europe. This could be a particularly useful tool, given that, as the European Commission states in The EU Startup and Scaleup Strategy Choose Europe to start and scalealmost 30% of European unicorn companies moved outside the European Union between 2008 and 2021 and only 8% of global scale-ups are based in Europe.

In 2024, there were 15 000 funding rounds in the United States totalling €210 billion in investment, while there were 11 000 in Asia for a total of €70 billionEurope, meanwhile, had 9600 rounds with total financing of €57 billion, with the number of deals falling by 16% and total value by 8% compared to 2023.*

The United States saw a 4% increase in the number of deals and a 29% rise in total funding over the same period.

Venture capital investment in Italy in 2024 totalled €1.5 billion over 417 rounds, up 31% vs. 2023.

The Italian venture capital market is mainly focused on deeptech, software and life sciences, with €300 million invested over 62 rounds in 2024 in life sciences alone. A €12 million investment in Serenis, co-led by Angelini Ventures, was the biggest deal in the life sciences sector (and among the top five overall) in the third quarter of 2025.

*Venture capital report produced by Growth Capital and Italian Tech Alliance, in partnership with Cdp venture Capital Sgr.